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Gelsemium elegans

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Wnt (1) β-catenin (1)
By Research Areas:	Cancer (3) Inflammation/Immunology (1) Neurological Disease (2)

Inhibitors & Agonists

Natural
Products

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-N12576

Koumidine

Others Others

Koumidine is an alkaloid that can be isolated from Gelsemium elegans .

Koumidine	Others	Others
Koumidine is an alkaloid that can be isolated from Gelsemium elegans .

HY-N3186

N-Methoxyanhydrovobasinediol	Others	Others
N-Methoxyanhydrovobasinediol is an alkaloid that can be isolated from Gelsemium elegans. N-Methoxyanhydrovobasinediol can be used as a reference .

HY-N7507A

Sempervirine nitrate	Wnt β-catenin	Cancer
Sempervirine is an alkaloid derived from Gelsemium elegans Benth.. Sempervirine inhibits the proliferation of hepatocellular carcinoma (HCC) cells and induces apoptosis by regulating Wnt/β-catenin pathway .

HY-N4031

Humantenine

Others Others

Humantenine is a indole alkaloid compound isolated from Gelsemium elegans .
HY-N0969

(Z)-Akuammidine

19-(Z)-Akuammidine; (Z)-Rhazine

(Z)-Akuammidine ((Z)-Rhazine) is isolated from Gelsemium elegans .
HY-N1599

16-Epivoacarpine

16-epi-Voacarpine
Others Others

16-Epivoacarpine is a natural alkaloid isolated from Gelsemium elegans .
HY-N3416

Koumine N-oxide

Others Others

Koumine N-oxide is an alkaloid compound isolated from the herb Gelsemium elegans .
HY-N1020

11-Hydroxyrankinidine

11-Hydroxyrankinidine is an alkaloid compound isolated from the whole plant of Gelsemium elegans .
HY-N0388

Gelsemine

Others Neurological Disease

Gelsemine, an alkaloid from the Chinese herb Gelsemium elegans, is effective in mitigating chronic pain. Antinociceptive effects.
HY-N1019

11-Hydroxyhumantenine

N-Methyl-11-hydroxyrankinidine

11-Hydroxyhumantenine is an alkaloid compound isolated from the EtOH extract of the stems of Gelsemium elegans .
HY-N3939

Gelsempervine A

16-epi-Nb-Methylvoacarpine
Others Others

Gelsempervine A (16-epi-Nb-Methylvoacarpine) is a natural product that can be isolated from Gelsemium elegans .
HY-N8350

Uncarinic acid E

Others Cancer

Uncarinic acid E is a compound can be isolated from Gelsemium elegans BENTH and has anti-tumor activity .

Humantenine	Others	Others
Humantenine is a indole alkaloid compound isolated from Gelsemium elegans .

(Z)-Akuammidine 19-(Z)-Akuammidine; (Z)-Rhazine
(Z)-Akuammidine ((Z)-Rhazine) is isolated from Gelsemium elegans .

16-Epivoacarpine 16-epi-Voacarpine	Others	Others
16-Epivoacarpine is a natural alkaloid isolated from Gelsemium elegans .

Koumine N-oxide	Others	Others
Koumine N-oxide is an alkaloid compound isolated from the herb **Gelsemium elegans** .

11-Hydroxyrankinidine
11-Hydroxyrankinidine is an alkaloid compound isolated from the whole plant of Gelsemium elegans .

Gelsemine	Others	Neurological Disease
Gelsemine, an alkaloid from the Chinese herb Gelsemium elegans, is effective in mitigating chronic pain. Antinociceptive effects.

11-Hydroxyhumantenine N-Methyl-11-hydroxyrankinidine
11-Hydroxyhumantenine is an alkaloid compound isolated from the EtOH extract of the stems of Gelsemium elegans .

Gelsempervine A 16-epi-Nb-Methylvoacarpine	Others	Others
Gelsempervine A (16-epi-Nb-Methylvoacarpine) is a natural product that can be isolated from Gelsemium elegans .

Uncarinic acid E	Others	Cancer
Uncarinic acid E is a compound can be isolated from Gelsemium elegans BENTH and has anti-tumor activity .

HY-N4030

Humantenmine Gelsenicine	Others	Inflammation/Immunology
Humantenmine, a newalkaloid isolated from Gelsemium elegan Banth in China, has the potential for pain and rheumatic arthritis treatment .

HY-N1018

11-Hydroxygelsenicine

11-Hydroxygelsenicine is a 11-hydroxy-substituted gelsedine-type indole alkaloid compound isolated from the EtOH extract of the stems of Gelsemium elegans .

11-Hydroxygelsenicine
11-Hydroxygelsenicine is a 11-hydroxy-substituted gelsedine-type indole alkaloid compound isolated from the EtOH extract of the stems of Gelsemium elegans .

HY-N3940

Gelsevirine	Others	Neurological Disease Cancer
Gelsevirine is the major alkaloid in Gelsemium elegans with potent anxiolytic effects. The anxiolytic mechanism of Gelsevirine may be involved in the agonist action of the glycine receptor in the brain. Gelsevirine has anti-proliferation activity with IC₅₀ values of 1.41 mM and 1.22 mM for SW480 cells and MGC80-3 cells, respectively .

HY-N1440

Koumine
Koumine is an alkaloid separated from Gelsemium elegans, shows potent anti-tumor activity. Koumine up-regulates the Bax/Bcl-2 ratio and caspase-3 expression in human breast cancer cells . Koumine has anxiolytic, antistress, antipsoriatic, and analgesic activities , protects against the development of arthritis in Rheumatoid arthritis (RA) animal models .

16-Epivoacarpine 16-epi-Voacarpine	Alkaloids other families Classification of Application Fields Source classification Other Diseases Plants Disease Research Fields Indole Alkaloids	Others
16-Epivoacarpine is a natural alkaloid isolated from Gelsemium elegans .

Koumidine	Structural Classification Alkaloids Source classification Loganiaceae Plants Gelsemium eleganis (Gardn. et Champ.) Benth. Indole Alkaloids	Others
Koumidine is an alkaloid that can be isolated from Gelsemium elegans .

N-Methoxyanhydrovobasinediol	Structural Classification Alkaloids Pyrrole Alkaloids Source classification Loganiaceae Plants Gelsemium eleganis (Gardn. et Champ.) Benth.	Others
N-Methoxyanhydrovobasinediol is an alkaloid that can be isolated from Gelsemium elegans. N-Methoxyanhydrovobasinediol can be used as a reference .

Humantenine	Alkaloids Classification of Application Fields Source classification Other Diseases Loganiaceae Plants Gelsemium eleganis (Gardn. et Champ.) Benth. Disease Research Fields Indole Alkaloids	Others
Humantenine is a indole alkaloid compound isolated from Gelsemium elegans .

Koumine N-oxide	Structural Classification Alkaloids Source classification Loganiaceae Plants Gelsemium eleganis (Gardn. et Champ.) Benth. Indole Alkaloids	Others
Koumine N-oxide is an alkaloid compound isolated from the herb **Gelsemium elegans** .

Gelsemine	Alkaloids Pyrrole Alkaloids Source classification Loganiaceae Plants Gelsemium eleganis (Gardn. et Champ.) Benth.	Others
Gelsemine, an alkaloid from the Chinese herb Gelsemium elegans, is effective in mitigating chronic pain. Antinociceptive effects.

Gelsempervine A 16-epi-Nb-Methylvoacarpine	Structural Classification Alkaloids Source classification Pyridine Alkaloids Loganiaceae Plants Gelsemium eleganis (Gardn. et Champ.) Benth.	Others
Gelsempervine A (16-epi-Nb-Methylvoacarpine) is a natural product that can be isolated from Gelsemium elegans .

Uncarinic acid E	Uncaria rhynchophylla (Miq.) Miq. ex Havil. Triterpenes Structural Classification Terpenoids Source classification Rubiaceae Plants	Others
Uncarinic acid E is a compound can be isolated from Gelsemium elegans BENTH and has anti-tumor activity .

Humantenmine Gelsenicine	Alkaloids other families Classification of Application Fields Source classification Plants Disease Research Fields Inflammation/Immunology Indole Alkaloids	Others
Humantenmine, a newalkaloid isolated from Gelsemium elegan Banth in China, has the potential for pain and rheumatic arthritis treatment .

Gelsevirine	Alkaloids Source classification Loganiaceae Plants Gelsemium eleganis (Gardn. et Champ.) Benth. Indole Alkaloids	Others
Gelsevirine is the major alkaloid in Gelsemium elegans with potent anxiolytic effects. The anxiolytic mechanism of Gelsevirine may be involved in the agonist action of the glycine receptor in the brain. Gelsevirine has anti-proliferation activity with IC₅₀ values of 1.41 mM and 1.22 mM for SW480 cells and MGC80-3 cells, respectively .

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Gelsemium elegans

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